What to Know Before Mixing Medications

The Do’s And Don’ts of Mixing Prescriptions and Over the Counter Medicine

Why Medication Interactions Matter

When two or more medications are taken together, they can interact in ways that either enhance or reduce their effectiveness—or cause harmful side effects. For example:

• Antibiotics and Birth Control Pills: Certain antibiotics can decrease the effectiveness of birth control.
• Blood Thinners and Pain Relievers: Drugs like ibuprofen or aspirin can increase the risk of bleeding when combined with blood thinners like warfarin.
• Supplements and Prescription Drugs: Even natural supplements, such as St. John’s Wort, can interact with medications like antidepressants or birth control.
• Antidepressants + Migraine Medications: Can lead to serotonin syndrome, a potentially life-threatening condition with symptoms like rapid heart rate, confusion, or tremors.  If you use both types of medications, inform your doctor immediately if you experience unusual symptoms.
• OTC Cold Medications + High Blood Pressure: Decongestants can raise blood pressure, counteracting the effects of your medication. Opt for decongestant-free alternatives, like saline nasal sprays or antihistamines.

Dos of Mixing Medications

1. DO Keep a List of All Medications You Take
   Write down every prescription, OTC medication, and supplement you use. Share this list with your doctor and pharmacist regularly.
2. DO Read Labels Carefully
   Always check the labels for warnings about interactions. Many OTC medications, like cold and allergy remedies, can have hidden risks when combined with prescriptions.
3. DO Ask Your Pharmacist
   Your pharmacist is a medication expert! They can identify potential interactions and offer advice on timing your doses.
4. DO Stick to One Pharmacy
   Filling all your prescriptions at the same pharmacy helps ensure your pharmacist has a complete record of your medications to catch possible interactions.
5. DO Use Medication Apps
   There are apps available to track your medications and flag potential interactions. Ask your pharmacist for recommendations.

Don’ts of Mixing Medications

1. DON’T Mix Medications Without Professional Advice
   Even if two medications seem harmless on their own, they may cause problems when combined. Always consult your doctor or pharmacist first.
2. DON’T Take Medications with Alcohol
   Alcohol can amplify the effects of many medications, including sedatives, painkillers, and antihistamines, leading to drowsiness or dangerous side effects.
3. DON’T Ignore Symptoms of an Interaction
   Symptoms like dizziness, nausea, or confusion could indicate a harmful interaction. Contact your healthcare provider immediately if you notice these signs.
4. DON’T Stop Taking Medications Abruptly
   If you suspect a problem, consult your doctor before stopping any medication. Abrupt changes can lead to withdrawal symptoms or other complications.
5. DON’T Assume Natural Means Safe
   Herbal supplements can interact with medications just like synthetic drugs. Always disclose any supplements you take to your healthcare provider.